overview
Paget’s Disease of Bone (PAJ-its) disrupts your body’s normal recycling process, in which new bone tissue gradually replaces old bone tissue. Over time, the bones can become brittle and deformed. The pelvis, skull, spine, and legs are most commonly affected.
The risk of Paget’s disease of the bone increases with age and when family members have it. For reasons not known to doctors, in recent years the disease has become rarer and less severe in its development. Complications can include fractures, hearing loss, and pinched nerves in the spine.
Bisphosphonates – drugs used to strengthen bones weakened by osteoporosis – are the mainstay of treatment. Surgery may be required if there are complications. Paget’s disease of bone Treatment in Nizamabad
symptoms
Most people with Paget’s disease have no symptoms. When symptoms occur, bone pain is the most common complaint.
Because this disease causes your body to create new bone faster than normal, faster remodeling creates less organized and weaker bones than normal bone, which can lead to bone pain, deformities, and fractures.
The disease can affect only one or two areas of your body, or it can be generalized. Your signs and symptoms, if any, will depend on the part of your body affected.
Swimming pool. Paget’s pelvic bone disease can cause hip pain.
Skull. Bone growth in the skull can lead to hearing loss or headaches.
Spine. When your spine is affected, the nerve roots can compress. This can cause pain, tingling, and numbness in one arm or leg.
Leg. As the bones weaken, they can bend and bend your legs. The enlarged and deformed bones in your legs can put extra pressure on nearby joints, which can lead to osteoarthritis of the knee or hip. Paget’s disease of bone Treatment in Nizamabad
The reasons
The cause of Paget’s disease of the bone is unknown. Scientists suggest that a combination of environmental and genetic factors contribute to the disease. Several genes appear to be linked to the disease.
Some scientists believe that Paget’s disease of bone is related to a viral infection in your bone cells, but this theory is controversial. Paget’s disease of bone Treatment in Nizamabad
Risk factors
Factors that can increase your risk of Paget’s disease of the bone include:
- Age. People over 50 are most likely to develop the disease.
- Sex. Men are affected more frequently than women.
- National origin. Paget’s bone disease is more common in England, Scotland, Central Europe and Greece – as well as in countries settled by European immigrants. It is rare in Scandinavia and Asia.
- Family history. If you have a relative with Paget’s bone disease, you are more likely to develop the disease.